8 September 2025
By Stacy M. Brown
Contributing Writer
(The Washington Informer) — A sweeping review published in The Lancet Regional Health – Europe has drawn a direct line between mental health disorders and cardiovascular disease (CVD), showing that individuals living with psychiatric conditions face not only a higher risk of heart problems but also a shorter life expectancy.
The paper, authored by researchers from Emory University, the University of Copenhagen, the University of Leeds, and others, concludes that people with depression, schizophrenia, bipolar disorder, post-traumatic stress disorder (PTSD), and anxiety live 10 to 20 years less on average, mainly due to heart disease.
Review reveals link between mental health disorders and cardiovascular disease; those with psychiatric conditions face higher risk of heart problems.
Photo by Mental Health America/Pexels courtesy of Washington Informer
The analysis shows that the connection between mental health and cardiovascular disease is not one-directional. The stress of a heart attack or stroke can trigger psychiatric disorders, while psychiatric conditions themselves set the stage for heart disease.
The risks are striking as depression raises cardiovascular risk by 72 percent, schizophrenia by 95 percent, bipolar disorder by 57 percent, PTSD by 61 percent, and anxiety disorders by 41 percent.
“It is important to understand that stress, anxiety, and depression can affect your heart, just like other physical factors,” the paper noted, offering guidance for how doctors might begin crucial conversations with patients.
A Widespread Burden
One in four people will experience a mental health disorder in their lifetime, yet many go untreated and often receive poor cardiovascular care.
“Despite having more interactions with the health care system, they undergo fewer physical checkups and screenings and receive fewer diagnoses and treatments for CVD and its risk factors,” the authors reported.
According to 2023 U.S. survey data cited in the study, more than half of those who met the criteria for a mental health disorder had not received any treatment, with even lower rates among non-White populations.
Researchers identified a cluster of overlapping drivers – poverty, trauma, social disadvantage, substance use, and poor access to health care – that amplify the dual risks of mental illness and cardiovascular disease.
Lifestyle behaviors such as smoking, poor diet, physical inactivity, and disrupted sleep patterns are also more common among people with psychiatric conditions.
The biological picture is equally troubling.
Dysregulation of the stress response system, inflammation, and autonomic nervous system dysfunction are all pathways through which psychiatric disorders may accelerate cardiovascular decline.
“Dysregulation of stress reactivity can result in the development of neuropsychiatric illnesses, inflammation and other stress-related disease states,” according to an October 2018 report “Factors promoting vulnerability to dysregulated stress reactivity and stress-related disease,” published by the National Institutes of Health (NIH) National Library of Medicine.
Breaking the Cycle
The study calls for a fundamental shift in medical practice.
“For the best care, an integrated approach is needed to address the complex needs of this vulnerable population,” the authors wrote. “Such approach should offer enhanced support and interdisciplinary care encompassing mental, cardiovascular, and behavioral health, as well as consideration of the social needs and barriers to care.”
Among the interventions reviewed, exercise emerged as one of the most effective treatments, improving both mood and heart health. Evidence shows that physical activity can deliver improvements on par with or greater than medication or psychotherapy for depression.
Mind-body practices like yoga and mindfulness, while requiring more evaluation, also show promise for improving outcomes across both mental and cardiovascular health.
“A large number of studies show that yoga benefits many aspects of cardiovascular health,” said Hugh Calkins, M.D., director of the Cardiac Arrhythmia Service at Johns Hopkins. “There’s been a major shift in the last five years or so in the number of cardiologists and other professionals recognizing that these benefits are real.”
A Call to Integrate Care
The authors stressed that progress depends on health care systems breaking down the wall between physical and mental health.
For decades, treatment has been siloed, with psychiatrists focusing on the mind and cardiologists on the body. That separation, the study finds, has left millions vulnerable.
The authors argue for expanded insurance coverage, investment in housing and employment stability, and the inclusion of psychiatric patients in cardiovascular research.
Above all, they call for integrated care models that recognize the tight link between mental and cardiovascular health.
“Heart disease and depression are both widespread among the general population and often can occur simultaneously in the same individual. This relationship is much more than a coincidence. The relationship between heart disease and depression is bidirectional, meaning that each can increase the risk of developing the other,” according to The Heart Foundation. “People who are depressed develop heart disease at a higher percentage than the general population and people with no history of depression are at increased risk after a heart attack.”
Global Health Priority
The stakes are enormous.
The World Health Organization has set a 2025 target to reduce the global burden of cardiovascular disease, arguing that this goal cannot be reached without directly addressing the disparities faced by those with psychiatric disorders.
“Closing the disparity gap for individuals with mental health disorders would be consistent with the World Health Organization 2025 targets of reducing the global burden of CVD,” the researchers concluded. “Reducing these disparities would also uphold the rights of people with mental health disorders to achieve the highest possible level of health and to fully participate in society and the workforce.”
This article originally published in the September 8, 2025 print edition of The Louisiana Weekly newspaper.